¨Method 1 (n=13) =
Continuous microcatheter
t-PA infusion within
the clot randomly
¨Method 2 (n=28) = t-PA infusion with intermittent microwire placement for manipulation within the clot (t-PA was not delivered around the wire)
¨Method 3 (n=45) = Repeated
microcatheter
repositioning to distribute
t-PA throughout the clot
